NovelDICER1mutation as cause of multinodular goiter in children
نویسندگان
چکیده
منابع مشابه
Thyroid carcinoma in multinodular goiter
Background: It is suggested that hyperthyroidism protects against thyroid malignancy. It was suggested that the incidence of malignancy is lower in toxic multinodular goiters than in non-toxic multinodular goiters. Recent studies show controversies. Material and methods: The aim of this study is to determine the incidence and type of thyroid carcinoma in toxic and nontoxic multinodular goiter i...
متن کاملPathogenesis of Heterogeneity in Human Multinodular Goiter
Functional and morphologic heterogeneity ofhuman multinodular goiters was investigated in 300 samples from "cold" and "hot" regions of 20 goiters transplanted onto nude mice. Transplants were labeled with [Hjthymidine and radioiodine, while the host's thyroid-stimulating hormone (TSH) secretion was either stimulated or suppressed. Proliferation and function of follicular cells were assessed in ...
متن کاملTrace elements status in multinodular goiter.
Importance of iodine and selenium in thyroid metabolism is well known, but the roles of other essential trace elements including copper, zinc, manganese and iron on thyroid hormone homeostasis remain unclear. The aim of this study was to investigate the status of those trace elements in benign thyroid diseases and evaluate possible links between trace element concentrations and thyroid hormones...
متن کاملNeglected nontoxic multinodular goiter presented as a large neck mass
Large multinodular goiters, obvious to the naked eye, are rarely confronted by clinicians nowadays; yet they do have a place in the differential diagnosis of the neck masses. Due to the fact that 80% of the neck masses in adults are related to malignancy, the later should be ruled out.
متن کاملMultinodular Goiter Presenting as a Retropharyngeal Mass: a Case Report
usually presents as a non-tender anterior neck mass. Asymptomatic patients may be treated medically, which often reduces the size of the gland or avoids progression of the disease. Neglected or ineffectively treated cases may grow beyond the confines of the gland, which primarily occurs caudally into the mediastinum. Cranial extension of the goiter into the retropharygeal space is a very rare p...
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ژورنال
عنوان ژورنال: Head & Neck
سال: 2013
ISSN: 1043-3074
DOI: 10.1002/hed.23250